Abstract General Information

Title

INTRAINDIVIDUAL VARIATION IN VOIDING DIARIES OF CHILDREN WITH ENURESIS

Introduction and objective

Children with monosymptomatic nocturnal enuresis (MNE) are often requested to complete voiding diaries in the diagnostic process. There is no consensus on the optimal number of days of registration in the voiding diary that would allow correct patient characterization.
The aim of this study was to examine the intraindividual variation in the parameters yielded from voiding diaries and evaluate if one week of registration is sufficient when evaluating the nocturnal urine production (NUP) and maximum voided volume (MVV) in children with MNE.

Method

We analyzed 228 voiding diaries completed for 14 days from treatment naïve children aged 6 to 14 years with MNE. NUP was estimated by diaper weight and volume of first morning void. MVV was registered both including and excluding first morning void.

Results

We found no significant differences in terms of NUP and MVV between week one and two, between one week or 14 days of registration, or when comparing two and four days of daytime-registration. The coefficient of variation reflecting the intraindividual day-to-day variability for NUP during two weeks of registration was 23% (6% to 58%), and the coefficient of variation for MVV including and excluding first morning void was 16% (1% to 53%) and 18% (1% to 60%). When using the ICCS definitions, two children (2%) with reduced MVV and no nocturnal polyuria and two children (4%) with nocturnal polyuria and normal MVV changed characterization when comparing two weeks of registration with one week of registration.

Conclusion

One week of nighttime-registration and two days of daytime-registration is sufficient when completing a voiding diary to provide valid estimates of a child’s NUP and MVV.